Osteoporosis and Dental Health_Prolia


Since I was in my 60s, I have been taking osteoporosis medicine steadily because of the results of the medical examination. Then, since last year in 2022, I have been treated about osteoporosis by prolia injection regularly every six months.


Prolia(denosumab)was developed and is manufactured by Amgen, a biopharmaceutical company based in the United States. Prolia was specifically developed to address bone health issues, particularly osteoporosis and related conditions.

Prolia(denosumab) is a prescription medication used for the treatment of osteoporosis. Prolia works by inhibiting a protein called RANK ligand, which plays a role in the breakdown of bone tissue. By blocking this protein, Prolia helps to increase bone density and reduce the risk of fractures. It was approved by regulatory agencies such as the U.S. Food and Drug Administration (FDA)for clinical use.

Prolia(denosumab) has several positive effects and benefits, especially for individuals with conditions such as osteoporosis.


Prolia positive effects and benefits

  1. Increased Bone Density: Prolia is effective at increasing bone density and reducing the risk of fractures in individuals with osteoporosis. It works by inhibiting the activity of cells that break down bone tissue, leading to improved bone density.
  2. Fracture Risk Reduction: Prolia helps to decrease the risk of fractures, particularly vertebral fractures (fractures of the spine) and hip fractures, which are common and serious consequences of osteoporosis.
  3. Improved Bone Health: By increasing bone density and strength, Prolia contributes to overall bone health and can help prevent the debilitating effects of weakened bones.
  4. Long-Term Use: Prolia is administered as an injection every six months, making it convenient for patients who may find it difficult to adhere to daily or weekly medications.
  5. Reduced Osteoporosis Progression: Prolia can slow down the progression of bone loss associated with osteoporosis, potentially leading to a better quality of life and decreased medical complications.

Below are the side effects data from a key prolia clinical study.


Prolia Side Effects

Common Side Effects:

  1. Back pain
  2. Pain in arms or legs
  3. Muscle pain
  4. High cholesterol levels
  5. Bladder infection

Serious Side Effects:

  1. Hypocalcemia (low levels of calcium in the blood)
  2. Serious infections (such as skin, abdominal, urinary tract infections)
  3. Dermatologic reactions (skin problems like dermatitis, eczema, or rashes)
  4. Atypical femoral fractures (unusual fractures of the thigh bone)
  5. Osteonecrosis of the jaw (affects jaw bone tissue)

You can get more information through prolia website(https://www.prolia.com/).



My experience

As I  am getting older, my teeth is deteriorating. So I needed to have implants. In this process. I had bone transplants in my gums.

When I started treating implants, my dentist advised me to stop taking or injecting osteoporosis drugs. Because they had a negative effect on the implant process. So during the implant treatment, I stopped treating osteoporosis.

After that I was living well without any problems, my gums started to get inflamed about a month ago.

I thought it was simple gum inflammation. So I visited the local dentist to treat an inflammation.

At there I received laser treatment because the local dentist said my gum is stretched. But even after many days, the inflammation worsened and I couldn’t chew the food properly… 🙁

In the end, I visited the dentist at a big general hospital. And the dentist removed the inflammation on my gum. They found out that some fragments of the bone transplanted during the implant fell and caused inflammation.

The dentist suspected that some bone fragments that had been implanted during the implant may have fallen off and caused inflammation. And he said that it could be a side effect of the osteoporosis injection, and that it would be better not to get the injection until this inflammatory treatment.


The correlation between osteoporosis and dental health

Is there a correlation between osteoporosis and dental health? As a result of investigating this correlation in various places, it is said that there is the following correlation.

  1.  Tooth health depends on strong jawbones to support teeth. Weakening of the jawbone due to osteoporosis can lead to tooth loss and difficulties with dental treatments like implants.
  2. Osteoporosis-related bone loss can contribute to tooth loss, especially if the jawbone can’t provide adequate support.
  3. Osteoporosis increases the risk of bone fractures, which can affect the healing process after dental implant surgery. Adequate bone density is necessary to support dental implants successfully.
  4. Some medications used to treat osteoporosis, might have implications for dental health. Long-term use of these medications could potentially affect the jawbone and oral health in certain cases.
  5. Chronic inflammatory conditions, like periodontal (gum) disease, might have connections to systemic inflammation and bone health. There’s ongoing research exploring the links between oral health and overall inflammation.

It’s important to maintain good oral hygiene practices and regular dental check-ups to promote oral health, especially if you have osteoporosis or are at risk for it.

Healthy seniors
Healthy seniors



Let’s take good care of bones and live a senior life of traveling as much as you want!

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